The Core Four is the heart of your high-performance skincare routine — a complete, clinical-grade system curated by Papaya Skin Loft for deep repair, long-term collagen support, and visibly radiant skin.
This powerhouse collection includes the four most transformative serums from Osmosis MD, formulated to work synergistically to repair DNA damage, calm inflammation, boost cellular turnover, and rebuild the skin barrier from within.
A complimentary Mini Infuse Mist is included to enhance penetration and maximize the results of every serum.
This set is ideal for anyone seeking results-driven, luxury skincare that targets fine lines, acne, hormonal skin, discoloration, redness, sun damage, or overall skin imbalance. Safe for sensitive and acne-prone skin.
Includes:
StemFactorMD — Growth factor serum for collagen remodeling, firmness, and youthful radiance
RescueMD — Epidermal repair serum for inflammation, redness, rosacea, acne, and compromised skin
CatalystMD — DNA repair vitamin C serum for brightening, firming, and scar healing
CorrectMD — Retinaldehyde serum for gentle, daily cellular turnover + smoothing
Mini Infuse Mist (FREE) — Boosts penetration and accelerates serum performance
How to Use
Daily Ritual (AM/PM)
AM
Prep
Mist skin with Infuse to soften and enhance absorption.Repair + Rebuild
Apply StemFactorMD to clean, dry skin.Brighten + Strengthen
Follow with CatalystMD for DNA repair and antioxidant support.Hydrate + Finish
Continue with your moisturizer and SPF.
PM
Prep
Mist Infuse before serum application.Inflammation Reset
Apply RescueMD to soothe redness, irritation, or acne activity.Smooth + Refine
Layer with CorrectMD for gentle retinal renewal and improved texture.Seal In
Finish with moisturizer.
Papaya Notes
This set is the backbone of nearly every transformation inside Papaya Skin Loft. Pair with an activating mist every single time — your results will dramatically improve with Infuse or Boost.
For the full Papaya glow, layer The Core Four AM and PM daily for unmatched clarity, firmness, and radiance.

